Strength and Vitality

Heart and Bone Health Support | Menopause Relief Dietary Supplement | Safe Multi-Symptom Relief | Helps Reduce Hot Flashes, Night Sweats and Mood Swings*

MenoGuard is the most complete synbiotic (probiotics + natural supplements) on the market. Doctor-formulated to support healthy bone, joint and heart function, and the overall wellness of perimenopausal and menopausal women. MenoGuard combines 26 natural ingredients in one convenient formula to aid your microflora in combating bone loss, painful joints, and heart issues that are common to women in menopause.

Dr. John P. Konhilas’ research shows that hormonal changes in menopause impact heart health and risks for heart disease. Existing research also shows that menopause hormonal changes affect how your bones are replenished with calcium and osteoporosis risk. Menoguard combines menopause symptom relief with probiotics and natural supplements proven by research studies to improve bone and heart health. MenoGuard is a safe and effective all natural dietary supplement that is both drug free and hormone free. No prescription needed.

MenoGuard can help you keep your heart, bones, and joints healthy so that you can enjoy the best life has to offer.*

• Heart Health
• Bone Health
• Fatigue
• Hot Flashes
• Mood Swings
• Irritability
• Low Energy
• Gut Health and Digestion
• Osteoporosis
• Blood Pressure
• Menopausal Discomfort
• Cognitive Function

"We use only the purest natural ingredients, triple lab tested and sourced from the most reputable U.S. suppliers, because our health is worth it."

Key Ingredients

• MenoGuard Proprietary Probiotic Blend

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  MenoGuard includes our proprietary blend of premium quality probiotics sourced directly from DuPont Nutrition and Biosciences. Specifically identified and formulated by Dr. John P. Konhilas to address the symptoms of menopause.

  • Lactobacillus acidophilus La-14®

    Clinical and preclinical studies demonstrate protection In the studies below Tyndallized ( sterilized with heat) Lactobacillus Acidophilus strains have shown a positive impact in multiple studies (linked below) on the UV damage, moisture level, and appearance of wrinkles in mice and a positive impact on atopic dermatitis in human clinical studies. The interesting aspect of these studies is the outcomes are driven with probiotics that are no longer living (active). They were heat sterilized, which suggests that the benefits of probiotics may be present even if the particular strain does not fully survive transit through stomach acid. **

    • https://www.ncbi.nlm.nih.gov/pubmed/31017257
    • https://www.ncbi.nlm.nih.gov/pubmed/27446272
    • https://www.ncbi.nlm.nih.gov/pubmed/27108169
  • Bifidobacterium animalis ssp. Lactis 420 (B420™)

    Bifidobacterium animalis ssp. Lactis 420 has been one of the main strains of focus for our Research co-founder Dr. John Konhilas in his work at the University of Arizona. Dr. Konhilas has spent most of his career studying how the changes in heart health for menopausal women. His particular probiotic research on this specific substrain has demonstrated cardiac protective impacts of this strain in oral supplementation in mice. Dr. Konhilas continues to study Bifidobacterium animalis ssp. Lactis 420 (B420™) and will continue to publish as he works to uncover the mechanism of impact in estrogen metabolism, bone protection, and arthritis prevention possibilities of this probiotic. For this health and heart-protective potential, specifically studied in menopausal mice and the potential impact on the human microbiome of perimenopausal and menopausal women Bifidobacterium animalis ssp. Lactis 420 (B420™) is included in every current formulation from MenoLabs. **

    • https://www.ncbi.nlm.nih.gov/pubmed/28409534
  • Lactobacillus reuteri 1E1®

    Lactobacillus reuteri is a long-studied probiotic in numerous studies with multiple sub-strains. Our inclusion of it here is based on continuing research that suggests a gut-brain axis affected by hormones, which may impact anxiety and mood as well as studies that show the support for healthy bones and reduction in adipose tissue (fat). While the anxiety research is still taking place in mice, the bone loss study for older women was a double-blind placebo-controlled study showing the reduction of bone loss with oral supplementation of Lactobacillus reuteri. We also find the use of Lactobacillus reuteri in an aging mouse study to return the “glow of youth,” a fascinating first step in understanding the role the microbiome plays in overall health. **

    • https://www.ncbi.nlm.nih.gov/pubmed/29926979
    • https://www.ncbi.nlm.nih.gov/pubmed/30979031
    • https://www.ncbi.nlm.nih.gov/pubmed/31022413
    • https://www.ncbi.nlm.nih.gov/pubmed/30690795
    • https://www.ncbi.nlm.nih.gov/pubmed/29329013
    • https://www.ncbi.nlm.nih.gov/pubmed/24675231
  • Lactobacillus rhamnosus (ATCC 53103) GG

    Lactobacillus rhamnosus GG is one of the most widely used and studied probiotic supplements. It has been clinically shown to help promote and regulate digestive health in both children and adults. The GG stands for “Good Growth,” as it was shown to be resistant to both acid and bile. We are just beginning to understand the role a healthy microbiome plays in maintaining bone mineralization with early mammal studies being completed. Early studies show both the promise of L. rhamnosus GG in supporting bone health and some early safety testing in older adults.**

    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155824
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710820
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249962
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627629
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887186

  MenoGuard Proprietary Prebiotic Stabilizer

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  The MenoGuard Prebiotic blend is specifically formulated to stabilize and support the potential efficacy of the nutrient supplements and probiotics in our formulation.

  • Organic Jerusalem Artichoke (inulin)

    We have included a fiber prebiotic ( Organic Jerusalem Artichoke) which serves as a “food source” for the healthy gut bacteria in the capsule and in your digestive tract.*

    • https://www.ncbi.nlm.nih.gov/pubmed/30574426
    • https://www.ncbi.nlm.nih.gov/pubmed/31618817
    • https://www.ncbi.nlm.nih.gov/pubmed/31619641
  • Tocotrienols Complex (Palm Oil Derived)

    Shown to reduce risk of osteoporosis and increase bone health. Some studies suggest that Tocotrienols support eye health.*

    • http://palmoilis.mpob.gov.my/publications/POD/pod64-lau.pdf
    • http://palmoil.my/upload/P10_Prof_Dr_Ima_Nirwana.pdf
    • http://downloads.hindawi.com/journals/ecam/2012/372878.pdf
  • Calcium Carbonate

    Supports bone health, especially in post-menopausal women.*

    • https://go.gale.com/ps/i.do?v=2.1&it=r&sw=w&id=GALE%7CA131228424&prodId=AONE&sid=googleScholarFullText&userGroupName=azstatelibdev
    • https://annals.org/aim/article-abstract/707030
    • https://www.thieme-connect.com/products/ejournals/html/10.1055/s-2002-19967
    • https://onlinelibrary.wiley.com/doi/abs/10.5694/j.1326-5377.1993.tb137917.x
  • Organic Acacia Gum

    May support healthy weight.*

    • https://www.ncbi.nlm.nih.gov/pubmed/29558953
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851694/
    • https://healthresource.shaklee.com/wp-content/uploads/2014/03/Jensen-1993.pdf
  • Resveratrol

    Contains antioxidants which have anti-aging properties & support heart health.*

    • https://www.mdpi.com/2072-6643/9/1/27
    • https://www.ncbi.nlm.nih.gov/pubmed/11551494?dopt=Citation
    • https://www.ncbi.nlm.nih.gov/pubmed/15723279?dopt=Citation
    • https://www.ncbi.nlm.nih.gov/pubmed/30574426
  • Sunflower Lecithin

    May support blood pressure and cardiovascular health.*

    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757297/

  MenoGuard Support Supplements

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  • Red Clover - Hot Flashes

    Red Clover (Trifolium pratense) is a natural source of isoflavones that are metabolized by the body into phytoestrogens. For this reason, there is a long cultural history of use of Red Clover as a natural remedy for feminine health concerns, including symptoms of menopause. Numerous studies have shown the potential reduction of hot flashes, with some studies showing mixed results. However, a promising study from Denmark shows a strong result in reducing hot flashes (vasomotor symptoms) in a human, placebo-controlled study when Red Clover was supplemented in conjunction with a blend of Lactobacillus probiotics.* **

    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462345
    • https://www.ncbi.nlm.nih.gov/pubmed/28160855
    • https://www.ncbi.nlm.nih.gov/pubmed/26265926
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780855/#B117-medicina-55-00544
  • Chaste Tree Berry Extract - Menopause Symptom Support

    There is data to suggest that Chaste Tree Berry can be used as an alternative supportive hormonal therapy. Studies show that Chaste Tree Berry may be used to reduce the menstrual cycle and menopausal discomforts.*

    • https://www.semanticscholar.org/paper/Evaluation-of-estrogenic-activity-of-plant-extracts-Liu-Burdette/393a5b62a2388108b6ea78f4d75cac7ee05d5e23
    • http://www.acudoc.com/black_cohosh_and_chasteberry.PDF
    • https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0032-1328187.pdf
  • Dong Quai Root Extract - Menopause Symptom Support

    Like Chaste Tree Berry, studies suggest that Dong Quai Root is another alternative to hormonal therapy. It's possible that in combination, Dong Quai Root may help treat menopausal symptoms.*

    • https://www.semanticscholar.org/paper/Evaluation-of-estrogenic-activity-of-plant-extracts-Liu-Burdette/393a5b62a2388108b6ea78f4d75cac7ee05d5e23
    • https://journals.lww.com/menopausejournal/Abstract/2002/03000/Estrogenic_activity_of_herbs_commonly_used_as.10.aspx
    • https://journals.lww.com/menopausejournal/Abstract/2005/12060/Use_of_dong_quai__Angelica_sinensis__to_treat.15.aspx
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1780040/
  • Magnolia Bark Extract - Menopause Symptom Support

    Studies suggest that magnolia may be used to help with symptoms of menopause. More specifically, it may help treat anxiety, insomnia, irritability, and other ares of neurology affected by the hormonal fluctuations in menopause.*

    • https://europepmc.org/article/med/16957676
    • https://europepmc.org/article/med/21311416
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120238/
  • Danshen Extract Salvia Miltiorrhiza - Hot Flashes

    Supports heart health. There is some evidence that suggest that Danshen has antioxidative properties, meaning that it may supports anti-aging as well.*

    • https://www.ncbi.nlm.nih.gov/pubmed/31338034
    • https://www.ncbi.nlm.nih.gov/pubmed/31545239

  MenoGuard Nutritional Support Formulation

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  • Vitamin C (as zinc ascorbate)

    Loss of estrogen during menopause leads to an increase in oxidative stress leading to an increased risk for heart disease, vasomotor disturbances, and osteoporosis. Vitamin C supplementation was studied in a large clinical trial. Menopausal women supplementing their diets with Vitamin C had lower levels of oxidative stress markers and fewer strokes, better cognitive function compared to menopausal women not taking Vitamin C.*

    • https://www.ncbi.nlm.nih.gov/pubmed/15006283
    • https://www.ncbi.nlm.nih.gov/pubmed/17698683
    • https://www.ncbi.nlm.nih.gov/pubmed/24672185
    • https://www.ncbi.nlm.nih.gov/pubmed/19451353
    • https://www.ncbi.nlm.nih.gov/pubmed/30766465
  • Vitamin D3 (as cholecalciferol)

    Vitamin D deficiency is more prevalent in the elderly and menopause than younger, pre-menopausal population. Supplementation with Vit D3 results in greater circulating amounts than supplementation with D2. Vitamin D may work synergistically with estrogen to help menopausal symptoms.*

    • https://insights.ovid.com/crossref?an=00042192-201910000-00015
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764124/
    • https://academic.oup.com/jcem/article/93/8/3015/2598528
    • https://academic.oup.com/ajcn/article/72/3/690/4729361
    • https://www.bmj.com/content/326/7387/469
    • https://www.bmj.com/content/330/7498/1003.short
  • Vitamin K2 (MK7)

    Vitamin K2 is critical in regulating calcium metabolism and helps control where it is deposited in the body. Vitamin K2 “holds” calcium and therefore plays a role in keeping it out of arteries. Although bacteria naturally manufacture vitamin K2 in the colon, our society’s extensive overuse of antibiotics has resulted in a population with inadequate quantities of this vital fat-soluble vitamin. Vitamin K2 is particularly bio-available and is also critical to bone strength.*

    • https://www.ncbi.nlm.nih.gov/pubmed/21674202
    • https://www.ncbi.nlm.nih.gov/pubmed/28445289
    • https://www.ncbi.nlm.nih.gov/pubmed/23140417
    • https://www.ncbi.nlm.nih.gov/pubmed/23858094
  • Riboflavin (as Riboflavin-5-phosphate (coenzyme vitamin B2))

    Studies suggest that riboflavin may fight free radicals with antioxidants. Riboflavin deficiencies have been linked to cardiometabolic and osteoporosis risks, especially in menopausal women.*

    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133110/
    • https://patentimages.storage.googleapis.com/ee/b5/ee/16b0325a6405d4/US20040001817A1.pdf
    • https://patentimages.storage.googleapis.com/7d/45/d8/a519aa33a59720/US8747915.pdf
  • Vitamin B6 (as Pyridoxal-5-phosphate (coenzyme vitamin B6))

    Vitamin B6 is key to the inflammatory response, and vitamin B6 deficiency leads to auto-immune disease.*

    • https://www.frontiersin.org/articles/10.3389/fnut.2019.00048/full#h7
    • https://www.ncbi.nlm.nih.gov/pubmed?cmd=link&linkname=pubmed_pubmed_reviews&uid=29244251&log$=relatedreviews&logdbfrom=pmc
  • Methylated Folate (as L-5-methyltetrahydrofolate)

    Studies show that folate supports prevention of CVC and the growth of hair, skin, and nails. There are often larger defiencies in of CVC as we age.*

    • http://innermedica.com/drjasonlee/wp-content/uploads/sites/2/Ultramaintain-Plus-Study.pdf
    • https://open.library.ubc.ca/cIRcle/collections/ubctheses/24/items/1.0167325
  • Vitamin B12 (as methylcobalamin)

    Vitamin B12 is not made by plants or humans and instead is synthesized exclusively by bacteria and archaea. B vitamins, in general, are cofactors for the enzymes that are involved in the energy-producing metabolic pathways for carbohydrates, fats, and proteins. B vitamins play an important role in maintaining the functions of the nervous system. Vitamin B12 deficiency in aging and menopause. Menopause drives dysbiosis, which can shift the microbiome to species that consume B12, thereby reducing bioavailability. Supplementation with B12 remodels the gut microbial community as it is critical to bacterial function leading to the production of chemicals needed by the host.*

    • https://www.ncbi.nlm.nih.gov/pubmed/27368135/
    • https://www.ncbi.nlm.nih.gov/pubmed/27854316/
    • https://elifesciences.org/articles/37138
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260394/
  • Zinc (as zinc ascorbate)

    Supports the skin and anti-aging. There is some data that suggests that ascorbic acids can repair & prevent damage on the dermal layer. Studies also show that zinc ascorbate can possibly help regulate insulin intake, which acts as an agent to manage diabetes and related metabolic disorders.*

    • https://patentimages.storage.googleapis.com/5c/3a/88/a75129d26bffe1/US6217914.pdf
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695174/
  • Benfotiamine

    Benfotiamine is the lipophilic analogue to thiamine and has higher bioavailability after oral administration. Thiamine, and to the same extent, benfotiamine, acts as a coenzyme for several catalytic steps in the glycolytic pathway to prevent cell damage produced by hyperglycemia-induced production of excess reactive oxygen species (ROS) and accumulation of advanced glycation end products (AGE). Administration of benfotiamine to diabetic patients resulted in significant improvement in diabetic neuropathy as determined by polyneuropathy score or nerve conduction velocity. In addition, endothelial cells and retinal pericytes cultured with benfotiamine and thiamine were protected from high glucose-induced cell loss or apoptosis.*

    • http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15250036
    • http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15726875
    • http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8932990
    • http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11827434
    • http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8886748

Directions for Use

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Take two capsules daily with food, preferably in the A.M. For best results, daily use for a minimum of 60 days is important. To continue to help manage menopause symptoms, use daily ongoing.*

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